SPRO live terminal view, Spero Therapeutics, Inc.

SPRO · Live chart

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SPRO · Smart-money compositeas of Aug 14

+9NEUTRALsmart-money positioning

-100 short0+100 long

Insiderno insider cluster in the l...

Congressno congressional trade in t...

13F fundsLONG

Short volumeFINRA short-volume is not c...

1 of 4 families contributing

SPRO · Recent signals

TWO SIGMA INVESTMENTS, LP added +138% to SPRO (2026Q1)HIGHLONGJul 24

Q3-2025: Beat consensus by 49.0% - EPS $-0.13 vs $-0.255 estimateMEDIUMLONGJun 23

Q4-2025: Beat consensus by 359.8% - EPS $0.53 vs $-0.204 estimateMEDIUMLONGJun 23

Q1-2026: Beat consensus by 29.2% - EPS $-0.13 vs $-0.1836 estimateMEDIUMLONGMay 30

Beat consensus by 49.0% - EPS $-0.13 vs $-0.255 estimateMEDIUMLONGMay 30

Beat consensus by 359.8% - EPS $0.53 vs $-0.204 estimateMEDIUMLONGMay 30

Q2-2025: Beat consensus by 92.3% - EPS $-0.03 vs $-0.3876 estimateMEDIUMLONGMay 30

SPRO · Institutional holdersas of 2025Q4

RENAISSANCE TECHNOLOGIES LLC$3.0M-11.9%

RENAISSANCE TECHNOLOGIES LLC$2.8M-7.1%

RENAISSANCE TECHNOLOGIES LLC$2.7Mn/a

TWO SIGMA INVESTMENTS, LP$2.1M+137.7%

TWO SIGMA INVESTMENTS, LP$868K+654.2%

CITADEL ADVISORS LLC$170K+33.4%

Point72 Asset Management, L.P.$140K+36.9%

CITADEL ADVISORS LLC$103Kn/a

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