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IONIS PHARMACEUTICALS INC (IONS) research

IONIS PHARMACEUTICALS INC
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Sector
Biotechnology
Last price
$44.90
As of

IONIS PHARMACEUTICALS INC (IONS): 5 institutional managers tracked by Kresmion reported non-option positions in their 2026Q2 Form 13F filings, and the most recent SEC filing on record for the company is a Form 8-K filed 2026-09-04.

As of . Source: SEC EDGAR filings for IONS. Method and limitations.

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You are seeing 5 of 38 signals recorded on IONS since 2026-05-29.

The five above landed across 2 days. The other 33 were recorded on 4 other days. 30 of the 38 are institutional flow rows, which arrive in batches on filing days.

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Largest reported share positions in IONS (2026Q2)

Manager / securityMarket value% portfolioQoQ
TWO SIGMA INVESTMENTS, LPCUSIP 462222100 · 2026Q2$495.7M0.36%,
CITADEL ADVISORS LLCCUSIP 462222AF7 · 2026Q2$134.7M0.02%,
RENAISSANCE TECHNOLOGIES LLCCUSIP 462222100 · 2026Q2$44.4M0.06%,
D. E. Shaw & Co., Inc.CUSIP 462222100 · 2026Q2$23.6M0.01%,
MILLENNIUM MANAGEMENT LLCCUSIP 462222100 · 2026Q2$22.9M0.01%,
CITADEL ADVISORS LLCCUSIP 462222100 · 2026Q2$18.7M0.00%,

Quarterly SEC Form 13F disclosures from the managers Kresmion tracks, not a complete ownership ranking. Non-option holdings only; reported put and call positions are excluded. Different securities are labeled by CUSIP. Values are reporting-period snapshots, not current position values. Filings can arrive up to 45 days after quarter-end.

Recent SEC filings, IONS

IONS mentioned in Kresmion daily briefs

IONS against its peers

IONS's operating margin of -40.4% ranks in the 57th percentile of 14 Biotechnology sub-industry peers, fiscal periods ending between 2025-12-31 and 2026-03-31.

MetricIONSPeer medianPercentilen
Revenue FY944M USD88.0M USD9217
Operating margin-40.4%-163.6%5714
Net margin-40.4%-193.2%5714
Return on equity-78.0%-22.3%1122

Peers (24): IMVT, RYTM, ALKS, BLTE, CAI, SYRE, TGTX, CGON, PRAX, SRRK, ABVX, MIRM, CNTA, PCVX, IBRX, CRNX, ORKA, TVTX, KYMR, PTGX, COGT, CYTK, LGND, NUVL. Left out: BCHMY (no annual filing). Fiscal periods ending between 2025-12-31 and 2026-03-31. Every figure is one full fiscal year read from one annual filing (IONS: 10-K), reported in USD. Nothing is trailing twelve months and nothing is converted between currencies. Source: SEC EDGAR XBRL company facts (public domain); prices from Kresmion's daily equity market-data snapshot. Open the full comparison.

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